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DMAP1 (DNA Methyltransferase 1-Associated Protein 1, DNMAP1, DNMTAP1, DNMT1-Associated Protein 1, MAT1-Mediated Transcriptional Repressor)

DMAP1 (DNA Methyltransferase 1-Associated Protein 1, DNMAP1, DNMTAP1, DNMT1-Associated Protein 1, MAT1-Mediated Transcriptional Repressor)

Cat no: D8073-02A

Supplier: United States Biological
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DNA methyltransferases methylate the 5-position of cytosine in the context of CpG dinucleotides. DNA methylation is crucial for normal embryonic development, imprinting, and X-chromosome inactivation. DNA methyltransferase 1 associated protein (DMAP1) has been shown to interact directly with the N-terminus of DNA Methyltransferase 1 (Dnmt1) throughout DNA replication during S phase. DMAP1 has also been identified as a critical gene product in myotonic dystrophy. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blotting: 1:1000-1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D8073-02A
Reactivities: Human, Mouse, Zebrafish/Fish
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: As reported
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: DKFZp686L09142, EAF2, FLJ11543, KIAA1425, SWC4
Additional info: This antibody is specific for human DMAP1. Species Crossreactivity: Recognizes human. Other species have not been tested. Reactivity with mouse is likely owing to 25/25 identical residues between mouse DMAP1 and the peptide used for this production. May react with Zebrafish (22/25 identical residues).

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