logo
logo
DMBT1 (Deleted in Malignant Brain Tumors 1 Protein, Apactin, CRP-ductin, Glycoprotein 300, gp300, Hensin, Mucin-like Glycoprotein, Muclin, Vomeroglandin, p80, Crpd) (Carboxyfluorescein)

Cat no: D3449-59

DMBT1 (Deleted in Malignant Brain Tumors 1 Protein, Apactin, CRP-ductin, Glycoprotein 300, gp300, Hensin, Mucin-like Glycoprotein, Muclin, Vomeroglandin, p80, Crpd) (Carboxyfluorescein)

DMBT1 (Deleted in malignant brain tumor-1; also MUCLIN, Hensin, CRP-Ductin and gp300/350) is a 230-350kD member of the DMBT1 family of molecules. It is expressed by select cell types including macrophages, intestinal epithelium, and pancreatic acinar cells. DMBT1 is both a transmembrane (TM) and secreted protein, and possesses multiple activities that may be predicated on multimerization. It drives epithelial differentiation, binds Gm+ and Gm- bacteria, and associates with cytoskeletal actin. Mouse DMBT1 is a type I TM glycoprotein that is 2085aa in length. Its extracellular region contains eight SRCR repeats (aa31-980, plus 1510-1610), five CUB domains (aa1023-1490, plus 1633-1742), and a ZP segment (aa1751-1999). Multiple splice variants exist. There are deletions of aa584-733, 397-534, 593-731 and 2032-2085 (within the TM segment), plus an insertion of 11aa after Asp29. Over aa215-420, mouse DMBT1 shares 75% aa identity with human DMBT1.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nHybridoma:\nFusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, E. coli-derived, recombinant mouse DMBT1. \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

D3449-59

Size

100Tests

Applications

WB

Hosts

Rat

Reactivities

Mouse

Form

Supplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Carboxyfluorescein.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2B

Additional Info

Recognizes mouse DMBT1. Species sequence homology: human (75%).

Read more on Supplier website
Advertisehere
BMA Biomedicals Horizontal banner
BMA Biomedicals

Latest promotion FROM:

BMA Biomedicals
View promotion

Latest promotions

Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....

It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...

Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...