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DMC1 (Disrupted Meiotic cDNA 1 Homolog, dJ199H16.1, DMC 1, DMC1H, HsLim15, Meiotic Recombination Protein DMC1/LIM15 Homolog)

Cat no: D8075-01

DMC1 (Disrupted Meiotic cDNA 1 Homolog, dJ199H16.1, DMC 1, DMC1H, HsLim15, Meiotic Recombination Protein DMC1/LIM15 Homolog)

Rad51 and disrupted meiotic cDNA1 (Dmc1) are the two eukaryotic DNA recombinases that participate in homology search and strand exchange reactions during homologous recombination mediated DNA repair.\n\nCellular Localization: Nuclear\n\nApplications: \nSuitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

D8075-01

Size

100ug

Applications

IF, IP, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov

Form

Supplied as a liquid in PBS, pH 7.2.

P Type

Mab

Purity

Mouse ascites

Isotype

IgG2a

References

This product has been used in:Masson JY et al. The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. EMBO J 18:6552-60 (1999). <PUBMED:10562567>

Additional Info

Specific for DMC1 - does not crossreact with the related protein Rad51. Species Crossreactivity: Crossreacts with Human, Mouse, Rat and bovine. Not yet tested in other species.

Alternative Names

Disrupted Meiotic cDNA 1 Homolog, dJ199H16.1, DMC 1, DMC1H, HsLim15, Meiotic Recombination Protein DMC1/LIM15 Homolog

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