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DNA pol E 2 Peptide

DNA pol E 2 Peptide

Cat no: BS5700P


Supplier: Bioworld Technology, Inc.
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DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. Exonucleases involved in these processes include DNA polymerases, including DNA pol delta and E. DNA pol delta consists of two subunits-p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50. DNA pol delta can be regulated by cell cycle proteins. DNA pol E is a multiple subunit enzyme, the catalytic subunit of which is encoded by the POL2 gene. The exact reactions catalyzed by DNA pol delta and E on leading and lagging strands have not yet been elucidated.
Catalogue number: BS5700P
Applications: Block/Neutralize/Inhibit
Swiss prot: P56282
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide DNA pol E 2. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: DNA polymerase epsilon subunit 2; DNA polymerase II subunit 2; DNA polymerase epsilon subunit B; POLE2; DPE2; DNA pol E2; DNA pol EB; DNA pol E B; DNA polE2; DNApolE2; DNA polEB; DNApolEB;
Additional info: This peptide can be used with studies using BS5700 DNA pol E 2 pAb.

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