DOK5 (Docking Protein 5, Downstream Of Tyrosine Kinase 5, Insulin Receptor Substrate 6, IRS-6, IRS6, C20orf180)

Cat no: D8080-05C

Supplier: United States Biological

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DOK5 represent a new signaling protein which has a potential role in insulin and IGF-1 action. This is an adapter proteins involved in signal transduction. DOK5 genes expressed in T cells and its expression is highest in skeletal muscle. This protein is tyrosine-phosphorylated in response to insulin and IGF-1 in transfected cells, It neither associates with these Src homology 2 domains nor activates MAPK. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	D8080-05C
Reactivities:	Human
Hosts:	Rabbit
Applications:	ELISA
Size:	100ug
Form:	Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type:	Pab
Isotype:	IgG
Purity:	Purified by Protein G affinity chromatography.
References:	1. Favre C et al, Genes Immun. 2003 Jan; 4(1):40-5. 2. Cai D et al, J Biol Chem. 2003 Jul 11; 278(28):25323-30.
Additional info:	Recognizes human DOK5.

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DOK5 (Docking Protein 5, Downstream Of Tyrosine Kinase 5, Insulin Receptor Substrate 6, IRS-6, IRS6, C20orf180)

Cat no: D8080-05C

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