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Dopamine Receptor D1 (DRD1)

Dopamine Receptor D1 (DRD1)

Cat no: D9000-04L

Supplier: United States Biological
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D(1A) dopamine receptor (DRD1) belongs to the G-protein coupled receptor 1 family and it is one of the five types of dopamine receptors (D1-D5) (1). DRD1 is the most expressed dopamine receptor in central nervous system and it is involved in the regulation of neuronal growth & development, and modulation of dopamine receptor D2-mediated events. G protein coupled DRD1 activates adenylyl cyclase which leads to activation of cyclic AMP dependent protein kinases. Polymorphism of DRD1 gene has been implicated in bipolar I disorder and attention deficit hyperactivity disorder (ADHD) (1,2). Applications: Suitable for use in Western Blot, Flow Cytometry. Other applications not tested. Recommended Dilution: Western Blot: 1:20,000-50,000 Flow Cytometry: 1:85 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: D9000-04L
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Flow Cytometry, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Bob AJ et al. Am J Med Genet B Neuropsychiatr Genet. 5:34(1):67-72, 2005. 2. Serverino G et al. Am J Med Genet B Neuropsychiatr Genet. 134(1):37-38.2005.
Additional info: Recognizes human dopamine receptor.

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