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Dopamine Transporter (DAT)

Cat no: D9020-01C


Supplier: United States Biological
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Plasmalemmal neurotransmitter transporters sequester synaptic and peri-synaptic transmitter into presynaptic elements. The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. Levels of DAT protein expression are altered by chronic drug administration. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (Frozen): 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9020-01C
Reactivities: Human, Non-Human Primate
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid. Preservative free
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Erickson, J.D., et al., Proc. Natl. Acad. Sci. USA 93 (1996) 5166 - 5171. 2. Giros, B., et al., J. Pharmacol. Exptl. Ther. 56 (1991) 2139 - 2142. 3. Haycock, J.W., et al., J. Neurochem. 87 (2003) 574 - 585. 4. Wilson, J.M., et al., Nature Medicine 2 (1996) 699 - 703.
Additional info: Recognizes human Dopamine Transporter at ~88kD. Species Crossreactivity: primate

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