Specific for human recombinant PAPP-A and human endogenous PAPP-A from atherosclerotic tissue (dimeric form of PAPP-A). No cross-reactivity with human heterotetrameric complex of PAPP-A (PAPP-A/ proMBP).dPAPP-A immunoassays and immunoprecipitation. Recommended pairs for specific detection of dPAPP-A antigen (capture - detection): PAPP52 (Cat.# 4P41) - PAPP30, PAPP2 - 7A6 (Cat.# 4P41). Selective dPAPP-A immunodetection in Western blotting. MAbs PAPP2, PAPP7 and PAPP8 recognize dPAPP-A in non-reducing conditions. No cross-reaction with human heterotetrameric complex of PAPP-A (PAPP-A/proMBP) was shown for these MAbs in WB.
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