DR-4 Antibody

Cat no: 251951

Supplier: ABBIOTEC

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Description
Additional Information

HLA class II histocompatibility antigen, DRB1-4 beta chain (DR-4) is a heterodimer of an alpha and a beta subunit; also referred as MHC class II molecule. DR-4 binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accomodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases.

Catalogue number:	251951
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	P13760
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DR-4.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	HLA class II histocompatibility antigen, DRB1-4 beta chain; MHC class II antigen DRB1*4; DR-4; DR4; HLA-DRB1