DR3/TRAMP Antibody

Cat no: 250889

Supplier: ABBIOTEC

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Description
Additional Information

Tumor necrosis factor receptor superfamily member 25 (TRAMP/DR3 or Apoptosis-mediating receptor DR3) is the receptor for TNFSF12/APO3L/TWEAK. TRAMP interacts directly with the adapter TRADD. TRAMP mediates activatio of NFkB and induces apoptosis. TRAMP/DR3 plays a role in regulating lymphocyte homeostasis. TRAMP/DR3 forms homodimers to interact strongly via the death domains with TNFRSF1 and TRADD to activate the apoptosis and NFkB signaling cascades. DR3 is highly e, Xenopus/Amphibian,pressed in thymocytes and lymphocytes.

Catalogue number:	250889
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q93038
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N/C-term region of human TRAMP/DR3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Tumor necrosis factor receptor superfamily member 25; WSL-1 protein; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death domain receptor 3; WSL protein; Apoptosis-inducing receptor AIR; Apo-3; Lymphocyte-associated receptor of death; LARD; TNFRSF25; APO3; DDR3; DR3; TNFRSF12; WSL; WSL1