DR4 (Tumor Necrosis Factor Receptor Superfamily Member 10A, Death Receptor 4, TNF-related Apoptosis-inducing Ligand Receptor 1, TRAIL Receptor 1, TRAIL-R1, TNFRSF10A, APO2, CD261, TRAILR1)

Cat no: D9300-32D

Supplier: United States Biological

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DR4 is 56kD member 10A of the TNFR superfamily (TNFRSF10A), also known as TRAIL-R1, Apo-2, and CD261. It is expressed at low levels by activated T cells and some tumors. After TRAIL engagement, DR4 (TRAIL-R1), through activation of NF-kB, induces apoptosis in the TRAIL ligated cell. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	D9300-32D
Reactivities:	Human
Hosts:	Mouse
Applications:	Immunohistochemistry, Western Blot
Size:	50ug
Form:	Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type:	Mab
Isotype:	IgG1
Purity:	Purified by Protein G affinity chromatography.
Additional info:	Recognizes human TNFRSF10A.

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DR4 (Tumor Necrosis Factor Receptor Superfamily Member 10A, Death Receptor 4, TNF-related Apoptosis-inducing Ligand Receptor 1, TRAIL Receptor 1, TRAIL-R1, TNFRSF10A, APO2, CD261, TRAILR1)

Cat no: D9300-32D

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