Home  >  Products  >  DR5 (Apo2, Trail-R2, TRAIL Receptor2, Trick2, Killer, Death Receptor5, CD262, KILLER, KILLER/DR5, TNFRSF10B, TRANCE-R, TRICKB, Tumor Necrosis Factor Receptor Superfamily, Member 10b, ZTNFR9)
DR5 (Apo2, Trail-R2, TRAIL Receptor2, Trick2, Killer, Death Receptor5, CD262, KILLER, KILLER/DR5, TNFRSF10B, TRANCE-R, TRICKB, Tumor Necrosis Factor Receptor Superfamily, Member 10b, ZTNFR9)

DR5 (Apo2, Trail-R2, TRAIL Receptor2, Trick2, Killer, Death Receptor5, CD262, KILLER, KILLER/DR5, TNFRSF10B, TRANCE-R, TRICKB, Tumor Necrosis Factor Receptor Superfamily, Member 10b, ZTNFR9)

Cat no: D9300-54B

Supplier: United States Biological
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Tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL R2 or TRICK 2) or also termed death receptor 5 (DR5) is a type I membrane protein that contains a cytoplasmic death domain. It binds TRAIL and mediates apoptosis via intracellular adaptor molecule FADD/MORT 1 and activation of NF?B. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:500 Western Blot: 1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D9300-54B
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 1mg
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Pab
Purity: Purified by Protein G affinity chromatography.
References: Schneider, P. et al. (1997) FEBS Lett. 416,329-334. Walczak, H. et al. (1997) EMBO J. 16,5386-5397. Suliman, A. et al. (2001) Oncogene 20,2122-2133. Falschlehner, C. et al. (2007) Int. J. Biochem. Cell Biol. 39,1462-1475.
Additional info: Recognizes human TRAIL R2

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