Home  >  Products  >  DR5 (Tumor Necrosis Factor Receptor Superfamily Member 10B, Death Receptor 5, TNF-related Apoptosis-inducing Ligand Receptor 2, TRAIL Receptor 2, TRAIL-R2, CD262, TNFRSF10B, KILLER, TRAILR2, TRICK2, ZTNFR9, UNQ160/PRO186)
DR5 (Tumor Necrosis Factor Receptor Superfamily Member 10B, Death Receptor 5, TNF-related Apoptosis-inducing Ligand Receptor 2, TRAIL Receptor 2, TRAIL-R2, CD262, TNFRSF10B, KILLER, TRAILR2, TRICK2, ZTNFR9, UNQ160/PRO186)

DR5 (Tumor Necrosis Factor Receptor Superfamily Member 10B, Death Receptor 5, TNF-related Apoptosis-inducing Ligand Receptor 2, TRAIL Receptor 2, TRAIL-R2, CD262, TNFRSF10B, KILLER, TRAILR2, TRICK2, ZTNFR9, UNQ160/PRO186)

Cat no: D9300-51N

Supplier: United States Biological
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DR5 is 55kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-a, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9300-51N
Reactivities: Human
Hosts: Rabbit
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes human DR5.

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