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DR6, Recombinant, Mouse:Fc (Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21)

DR6, Recombinant, Mouse:Fc (Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21)

Cat no: 044765

Supplier: United States Biological
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DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6. Sequence: Mouse DR6 (aa 42-348) is fused at the C-terminus to the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 6 months after receipt when stored at -20 degrees C.
Catalogue number: 044765
Size: 50ug
Form: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Purity: >95% (SDS-PAGE)
Alternative names: Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21

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