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DSCAM (Down Syndrome Cell Adhesion Molecule)

Cat no: D9635-51

DSCAM (Down Syndrome Cell Adhesion Molecule)

DSCAM (Down syndrome cell adhesion molecule) is a 230 kD axonal guidance molecule that is a member of the Ig superfamily. It is synthesized as a mature, 2005 amino acid (aa) type I transmembrane glycoprotein. There is a large, 1578 aa extracellular domain (ECD) and a 389 aa cytoplasmic region. The ECD shows ten C2-type Ig-like domains and six fibronectin type III repeats. One soluble splice form is known which contains all the ECD modules and ends after aa # 1571 of the precursor. This form has a unique C-terminal ten amino acids. DSCAM is found on axonal and dendritic processes. It also forms homophilic complexes among cells. \nOverexpression is associated with Down

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SPECIFICATIONS

Catalog Number

D9635-51

Size

100ug

Applications

ELISA, ICC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile ddH2O or sterile 40-50% glycerol.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2b

Additional Info

Recognizes human DSCAM.

Read more on Supplier website

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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