DSPP, NT (DSPP, Dentin sialophosphoprotein, Dentin phosphoprotein, Dentin phosphophoryn, Dentin sialoprotein) (APC)

This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq].\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

034832-APC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)\nBai, H., et al. BMC Med. Genet. 11, 23 (2010) :\nKida, M., et al. Eur. J. Oral Sci. 117(6):691-694(2009)\nWheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :\nQu, E.J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26(5):536-538(2009)

Additional Info

Human

Alternative Names

DSPP, Dentin sialophosphoprotein, Dentin phosphoprotein, Dentin phosphophoryn, Dentin sialoprotein