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DSS1 (Deleted in Split-Hand/Split-Foot 1 Region, Split Hand/Foot Malformation Type 1, SHFD1, ECD, SEM1, SHSF1, Shfdg1)

DSS1 (Deleted in Split-Hand/Split-Foot 1 Region, Split Hand/Foot Malformation Type 1, SHFD1, ECD, SEM1, SHSF1, Shfdg1)

Cat no: D9642-01B

Supplier: United States Biological
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The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:32,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9642-01B
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: split hand/foot malformation type 1, deleted in split-hand/split-foot 1, deleted in split-hand/foot 1, candidate for split hand/foot malformation type 1, Shfdg1, SHSF1, SHFD1, SEM1, ECD, Deleted in split-hand/split-foot 1 region, DSS1, split hand/foot malformation (ectrodactyly) type 1, SHFM1
References: 1. Wei SJ, Trempus CS, Cannon RE, Bortner CD, Tennant RW. Identification of Dss1 as a 12-O-Tetradecanoylphorbol-13-acetate-responsive Gene Expressed in Keratinocyte Progenitor Cells, with Possible Involvement in Early Skin Tumorigenesis.J Biol Chem. 2003 Jan 17;278(3):1758-68.
Additional info: Recognizes SHFM1. Species sequence homology: human, mouse, bovine, porcine.

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