Home  >  Products  >  DUOX1 (Dual Oxidase 1, Flavoprotein NADPH Oxidase, Large NOX 1, Long NOX 1, LNOX1, MGC138840, MGC138841, NADPH Thyroid Oxidase 1, Nicotinamide Adenine Dinucleotide Phosphate Oxidase, NOXEF1, Thyroid Oxidase 1, THOX1)
DUOX1 (Dual Oxidase 1, Flavoprotein NADPH Oxidase, Large NOX 1, Long NOX 1, LNOX1, MGC138840, MGC138841, NADPH Thyroid Oxidase 1, Nicotinamide Adenine Dinucleotide Phosphate Oxidase, NOXEF1, Thyroid Oxidase 1, THOX1)

DUOX1 (Dual Oxidase 1, Flavoprotein NADPH Oxidase, Large NOX 1, Long NOX 1, LNOX1, MGC138840, MGC138841, NADPH Thyroid Oxidase 1, Nicotinamide Adenine Dinucleotide Phosphate Oxidase, NOXEF1, Thyroid Oxidase 1, THOX1)

Cat no: D9837-50

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq] Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D9837-50
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Dual Oxidase 1 Precursor, EC=1.11.1, EC=1.6.3.1
References: Harper RW, Xu C, Eiserich JP, et al. Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium. FEBS Lett. 2005 Aug 29;579(21):4911-7. PMID: 16111680.
Additional info: Recognizes human DUOX1.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave