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DUSP13 (Dual Specificity Phosphatase 13, BEDP, Dual Specificity Phosphatase SKRP4, FLJ32450, MDSP, Testis-and Skeletal-muscle-specific DSP, TMDP)

DUSP13 (Dual Specificity Phosphatase 13, BEDP, Dual Specificity Phosphatase SKRP4, FLJ32450, MDSP, Testis-and Skeletal-muscle-specific DSP, TMDP)

Cat no: D9840-46E

Supplier: United States Biological
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DUSP13, a novel DSP, is a member of highly conserved Protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation. DUSP13 consists of a conserved catalytic domain and is expressed specifically in the testis and skeletal muscle. Based on mRNA localization and expression studies during development, DUSP13 is suggested to be expressed as 3 isoforms due to alternative splicing. Reports suggest DUSP13 might be involved in the regulation of meiosis and differentiation of testicular germ cells during spermatogenesis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human skeletal muscle lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9840-46E
Reactivities: Human, Mouse, Bovine, Canine
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity Chromatography.
References: 1. Nakamura et.al Biochem J 344; 819-825 (1999). 2. Chen et.al JBC 279 (40) 41404-41413 (October 1, 2004).
Additional info: Recognizes human DUSP13 (isoforms 1, 2 and 3). Species Crossreactivity: bovine, chimpanzee, canine, rhesus monkey. Species sequence homology: mouse and rat.

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