Home  >  Products  >  DUSP16, NT (Dual Specificity Protein Phosphatase 16, KIAA1700, Mitogen-activated Protein Kinase Phosphatase 7, MAP Kinase Phosphatase 7, MKP7, MKP-7)
DUSP16, NT (Dual Specificity Protein Phosphatase 16, KIAA1700, Mitogen-activated Protein Kinase Phosphatase 7, MAP Kinase Phosphatase 7, MKP7, MKP-7)

DUSP16, NT (Dual Specificity Protein Phosphatase 16, KIAA1700, Mitogen-activated Protein Kinase Phosphatase 7, MAP Kinase Phosphatase 7, MKP7, MKP-7)

Cat no: D9840-52F

Supplier: United States Biological
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DUSP16 is involved in the inactivation of MAP kinases. The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9840-52F
Reactivities: Human
Hosts: Goat
Applications: ELISA, Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in 0.5mg/ml TBS, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by ammonium sulfate precipitation.
Alternative names: Dual Specificity Phosphatase 16, EC=3.1.3.16, EC=3.1.3.48, FLJ36298, FLJ40991, MGC129701, MGC129702
Additional info: Recognizes human DUSP16.

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