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DUSP8 (Dual Specificity Protein Phosphatase 8, Dual Specificity Protein Phosphatase hVH-5)

Cat no: 136048

DUSP8 (Dual Specificity Protein Phosphatase 8, Dual Specificity Protein Phosphatase hVH-5)

DUSP8 encodes a dual specificity MAP kinase phosphatase which has been shown to hydrolyze p-nitrophenylphosphate and inactivate mitogen-activated protein kinases in vitro. The mouse homologue, M3/6, has been demonstrated to be uniquely specific for JNK and p38 kinases. DUSP8 has been mapped to 11p15, a chromosomal region that has been implicated in the development of a number of tumor types, including lung which is a tissue known to express this gene, and loss of heterozygosity has been found in one of eight informative lung tumors studied. The presence of a CG-rich trinucleotide repeat in the coding region has been suggested to be a possible target for mutation which might result in loss of function or altered properties.\n\nApplications: \nSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:1000\nWestern Blot: 1:100-1:500\nImmunohistochemistry (Paraffin): 10ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

136048

Size

50ug

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Additional Info

Recognizes human DUSP8.

Read more on Supplier website

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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