Dynamin 1 (DNM, Dynamin-1)

Supplier:

United States Biological

Cat no: D9900-02D

Dynamin 1 (DNM, Dynamin-1)

Dynamin 1, also known as DNM1, is a human gene. This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:1000\nOptimal dilutions to be determined by the researcher.\n\nPositive Control: \nRat Brain Cytosol Lysate.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

D9900-02D

Size

100ug

Applications

WB

Hosts

Sheep

Reactivities

Hum, Mouse, Rat, Can

Form

Supplied as a liquid in 0.1M Tris-Glycine, pH7.4, 15mM sodium chloride, 0.05% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

Additional Info

Recognizes Dynamin 1 (765-778). Species Crossreactivity: rat, mouse, human. Species sequence homology: canine.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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