Home  >  Products  >  Dynamin-1-like Protein (DNM1L, Dynamin Related Protein 1, DRP1, EC 3.6.5.5, Dynamin-like Protein, Dnm1p/Vps1p-like Protein, DVLP)
Dynamin-1-like Protein (DNM1L, Dynamin Related Protein 1, DRP1, EC 3.6.5.5, Dynamin-like Protein, Dnm1p/Vps1p-like Protein, DVLP)

Dynamin-1-like Protein (DNM1L, Dynamin Related Protein 1, DRP1, EC 3.6.5.5, Dynamin-like Protein, Dnm1p/Vps1p-like Protein, DVLP)

Cat no: D9901-30

Supplier: United States Biological
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A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses. Cellular Localization: Cytoplasm; cytosol. Intracytoplasmic membrane; peripheral mambrane protein. Mainly cytosolic. Also membrane-associated. Localizes to mitochondia at spots of division events. Associated with peroxisomal membranes, it is recruited in part by PEX11B. May also be associated with endoplasmic reticulum tubules and cytoplasmic vesicles and found to be perinuclear. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D9901-30
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: Dynamin Family Member Proline-rich Carboxyl-terminal Domain less, Dymple, Dynamin-related Protein 1, Dynamin-like Protein 4, Dynamin-like Protein IV, HdynIV
Additional info: Species Crossreactivity: This antibody reacts with the human and mouse protein. It has not been tested against any other species.

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