Home  >  Products  >  Dynamin-1-like Protein (DNM1L, Dynamin Related Protein 1, DRP1, EC 3.6.5.5, Dynamin-like Protein, Dnm1p/Vps1p-like Protein, DVLP)
Dynamin-1-like Protein (DNM1L, Dynamin Related Protein 1, DRP1, EC 3.6.5.5, Dynamin-like Protein, Dnm1p/Vps1p-like Protein, DVLP)

Dynamin-1-like Protein (DNM1L, Dynamin Related Protein 1, DRP1, EC 3.6.5.5, Dynamin-like Protein, Dnm1p/Vps1p-like Protein, DVLP)

Cat no: D9901-30B

Supplier: United States Biological
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A human dynamin-related protein, DRP1, contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses. Cellular Localization: Cytoplasm; cytosol. Intracytoplasmic membrane; peripheral mambrane protein. Mainly cytosolic. Also membrane-associated. Localizes to mitochondia at spots of division events. Associated with peroxisomal membranes, it is recruited in part by PEX11B. May also be associtaed with endoplasmic reticulum tubules and cytoplasmic vesicles and gound to be perinuclear. Applications: Suitable for use in Western Blot and Immunohistochemistry (paraffin). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9901-30B
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in Tris-glycine saline (TGS) containing 0.05% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: Dynamin Family Member Proline-rich Carboxyl-terminal Domain less, Dymple, Dynamin-related Protein 1, Dynamin-like Protein 4, Dynamin-like Protein IV, HdynIV
Additional info: Recognizes human DRP1. Shows a band at ~81kD in Western Blot. Species Crossreactivity: bovine, mouse, primate and rat.

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