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Dynein (Cytoplasmic 1, Heavy Chain 1, DYNC1H1)

Dynein (Cytoplasmic 1, Heavy Chain 1, DYNC1H1)

Cat no: D9901-51

Supplier: United States Biological
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Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:4000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: D9901-51
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: dynein, cytoplasmic-like, dynein, cytoplasmic, heavy polypeptide 1, dynein heavy chain, cytosolic, cytoplasmic dynein heavy chain, DYNC1H1 variant protein, p22, KIAA0325, HL-3, Dnchc1, DYHC, DNECL, DNCL, DNCH1, DKFZp686P2245, DHC1a, DHC1, dynein, cytoplasmic 1, heavy chain 1, DYNC1H1
References: 1. Chen XJ, Levedakou EN, Millen KJ, Wollmann RL, Soliven B, Popko B Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene J Neurosci. 2007 Dec 26;27(52):14515-24
Additional info: Recognizes DYNC1H1. Species sequence homology: human, rat.

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