Home  >  Products  >  E6AP, exon 7 (hPV, HPVE6AP, EPVE6AP, Human papillomavirus E6-associated protein, UBE3A, Ubiquitin-protein ligase E3A, AS, Angelman Syndrome, ANCR)
E6AP, exon 7 (hPV, HPVE6AP, EPVE6AP, Human papillomavirus E6-associated protein, UBE3A, Ubiquitin-protein ligase E3A, AS, Angelman Syndrome, ANCR)

E6AP, exon 7 (hPV, HPVE6AP, EPVE6AP, Human papillomavirus E6-associated protein, UBE3A, Ubiquitin-protein ligase E3A, AS, Angelman Syndrome, ANCR)

Cat no: E0015-02A

Supplier: United States Biological
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E6AP was originally identified as the ubiquitin-protein ligase involved in human papillomavirus E6-mediated p53 degradation. It has since been shown to act as an E3 ubiquitin-protein ligase catalyzing the ubiquitination of several other protein substrates. Ubiquitin E3 ligases are overexpressed in many human cancers and their inhibition leads to growth suppression or apoptosis. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: E0015-02A
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7.5, 0.09% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: hPV, HPVE6AP, EPVE6AP, Human papillomavirus E6-associated protein, UBE3A, Ubiquitin-protein ligase E3A, AS, Angelman Syndrome, ANCR
Additional info: Recognizes human E6AP. Species Crossreactivity: mouse. Reactivity with Xenopus laevis UBE3A is likely owing to sequence homology with the immunogen used for this antibody.

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