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EB 47

Cat no: 011031


Supplier: United States Biological
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EB 47 is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Poly(ADP-ribose) polymerases (PARPs) play a major role in cellular survival and maintenance of energy stores after genotoxic insult.
Catalogue number: 011031
Size: 10mg
Alternative names: 5'-Deoxy-5'-[4-[2-[(2,3-dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine Dihydrochloride; 4-[1-(6-Amino-9H-purin-9-yl)-1-deoxy-b-D- ribofuranuronoyl]-N-(2,3-dihydro-1-oxo-1H-isoindol-4-yl)-1-piperazineacetamide Dihydrochloride;
References: Jagtap, et al.: Bioorg. Med. Chem. Lett., 14, 81 (2004), Gaymes, et al.: Haematologica, 94, 638 (2009), Ferraris, et al.: J. Med. Chem. 53, 4561 (2010),

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