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EBI3 (IL-27/EBI3, Epstein-Barr Virus Induced Gene-3, IL-35/EBI3, IL-27 EBI3 Subunit)

Cat no: 142860

EBI3 (IL-27/EBI3, Epstein-Barr Virus Induced Gene-3, IL-35/EBI3, IL-27 EBI3 Subunit)

Epstein-Barr Virus Induced Gene-3 (EBI3), is a secreted glycoprotein belonging to the hematopoietin receptor family and is related to the p40 subunit of IL-12. EBI3 was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. Human EBI3, as a non-glycosylated protein, consists of 209 amino acids and has a molecular weight of 23.3kD.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution: \nWestern Blot: 1:1000\nOptimal dilutions to be determined by the researcher.\n\nEndotoxin: \n<0.1EUs/ug\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

142860

Size

100ug

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a lyophilized powder in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. No preservatives or stabilizers added.

P Type

Pab

Purity

Purified Ig fraction

Isotype

IgG

Additional Info

Recognizes human IL-27/EBI3.

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