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Products Ebselen (2-Phenyl-1,2-benzisoselenazol-3-(2H)-one)
| Catalogue number: | 044768 |
| Size: | 1mg |
| Purity: | >98% (NMR) |
| Alternative names: | 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one |
| References: | Product Reference: ?A novel biologically active seleno-organic compound--III. Effects of PZ 51 (Ebselen) on glutathione peroxidase and secretory activities of mouse macrophages: M.J. Parnham & S. Kindt; Biochem. Pharmacol. 33, 3247 (1984) ?Seleno-organic compounds and the therapy of hydroperoxide-linked pathological conditions: M.J. Parnham & E. Graf; Biochem. Pharmacol. 36, 3095 (1987) ?Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51): M. Maiorino, et al.; Biochem. Pharmacol. 37, 2267 (1988) ?Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite: H. Sies & H. Masumoto; Adv. Pharmacol.38, 229 (1997) ?Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis: Y. Nakamura, et al.; J. Biol. Chem. 277, 2687 (2002) ?Molecular actions of ebselen-an antiinflammatory antioxidant: T. Schewe; Gen. Pharmacol. 26, 1153 (1995) ?Studies on the anti-inflammatory activity of ebselen. Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C?: I.A. Cotgreave, et al.; Biochem. Pharmacol. 38, 649 (1989) ?Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione: C. Schewe, et al.; Biochem. Pharmacol. 48, 65 (1994) ?Evaluation of the antifungal and plasma membrane H+-ATPase inhibitory action of ebselen and two ebselen analogs in S. cerevisiae cultures: B. Billack, et al.; J. Enzyme Inhib. Med. Chem. 25, 312 (2010) ?Ebselen: a thioredoxin reductase-dependent catalyst for alpha-tocopherol quinone reduction: J. Fang, et al.; Toxicol. Appl. Pharmacol. 207, 103 (2005) ? |
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