Home  >  Products  >  Ectonucleoside Triphosphate Diphosphohydrolase 5 (ENTPD5, CD39 Antigen-like 4, CD39L4, ER-UDPase, MGC163357, MGC163359, NTPDase-5, PCPH)

Ectonucleoside Triphosphate Diphosphohydrolase 5 (ENTPD5, CD39 Antigen-like 4, CD39L4, ER-UDPase, MGC163357, MGC163359, NTPDase-5, PCPH)

Cat no: E2058-50A


Supplier: United States Biological
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The ecto-nucleoside triphosphate diphosphohydrolases (eNTPDases) are a family of enzymes that control extracellular nucleotide levels, thereby regulating purinergically controlled physiological processes. Six of the eight known NTPDases are membrane-bound, and only ENTPD5 and ENTPD6 can be released as soluble enzymes (1). ENTPD5 promotes reglycosylation reactions involved in glycoproteins folding and quality control in the endoplasmic reticulum. It also hydrolyzes UDP, GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate (2). ENTPD5 is expressed in adult liver, kidney, prostate, testis and colon (1). Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-1:10,000 Immunohistochemistry (Paraffin): 1:100-1:250 Immunoprecipitation: 1:10-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: E2058-50A
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Murphy-Piedmonte DM, et al. Proteins and proteomics 1747:251-259, 2005, 2. The UniProt Consortium, The Universal Protein Resource (UniProt), Nucleic Acids Res. 36:D190-D195 (2010)
Additional info: Recognizes human ENTPD5 at ~47kD. Species Crossreactivity: rmouse, rat.

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