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EDG-3 (EDG3, S1P3, Sphingosine 1-phosphate Receptor-3, LPB3, S1PR3) (APC)

Cat no: 145450

EDG-3 (EDG3, S1P3, Sphingosine 1-phosphate Receptor-3, LPB3, S1PR3) (APC)

Sphingosine 1-phosphate receptor-3 (S1P3); also known as EDG-3, is a 378 amino acid (aa) seven transmembrane receptor for the lysolipid phosphoric acid mediator, sphingosine 1-phosphate (S1P). Interactions between S1P3 and S1P induce a range of responses including vasoconstriction, brachycardia, vascular endothelial and smooth muscle cell proliferation and migration, heart and liver fibrosis, and coagulation-induced inflammation. Extracellular portions of human S1P3 show 74% aa sequence identity with mouse and rat S1P3.\n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nMouse myeloma cells with B cells from Balb/c mice.\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for at 12 months at 4 degrees C. Freezing allophycocyanin conjugates will result in a substantial loss of activity. Allophycocyaninconjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

145450

Size

100Tests

Applications

FC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).

P Type

Mab

Purity

Purified by Protein A or G affinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes human S1P3/EDG-3.

Read more on Supplier website

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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