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EGFR, CT (Epidermal Growth Factor Receptor, Proto-oncogene c-ErbB-1, Receptor Tyrosine-protein Kinase erbB-1, ERBB1)

Cat no: E3375-03P

EGFR, CT (Epidermal Growth Factor Receptor, Proto-oncogene c-ErbB-1, Receptor Tyrosine-protein Kinase erbB-1, ERBB1)

EGFR (epidermal growth factor receptor) is expressed in nearly all tissues of the zebrafish. Its counterpart, EGF (epidermal growth factor) is expressed within the ovary and testis. Within the ovaries, EGFR expression is limited to follicle cells, suggesting that it plays a role in regulation of follicle cells by oocytes expressing EGF. Zebrafish are particularly well suited to animal model studies of the cardiovascular system due to their transparent physiology in the embryo stage. A study of inhibition of zebrafish EGRF showed that it has a crucial role in cardiovascular function, as evidenced by resulting defects.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:500-1:1000\nELISA: 1:5000-1:20,000\nOptimal dilutions to be determined by the researcher.\n\nControl Peptide: E3375-03Q\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

E3375-03P

Size

250ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

ZF/Fish

Form

Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Wang, Y and Ge, W (2004) Biol. Reprod. 71(3): 749-760. 2. Goishi, K et al (2003) Mech. Dev. 120(7): 811-822.

Additional Info

Recognizes zebrafish EGFR.

Read more on Supplier website

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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