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EGFR (Epidermal Growth factor receptor, Proto-oncogene c-ErbB-1, Receptor Tyrosine-protein Kinase erbB-1, ERBB1)

Cat no: E3375-12D

EGFR (Epidermal Growth factor receptor, Proto-oncogene c-ErbB-1, Receptor Tyrosine-protein Kinase erbB-1, ERBB1)

Epidermal growth factor receptor (EGFR) is a tyrosine protein kinase comprised of two different components of different molecular weights. Both components contain phosphotyrosine and phosphothreonine but only the higher molecular weight component contains phosphoserine. EGFR signaling involves small GTPases of the Rho family and EGFR trafficking involves small GTPases of the Rab family. EGFR expression is widespread in both normal and cancerous tissues.\n\nApplications: \nSuitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Formalin-fixed, paraffin-embedded): 5ug/ml Immunocytochemistry: \nImmunoprecipitation: 10-12ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

E3375-12D

Size

50ug

Applications

ICC, IHC, IP, WB

Hosts

Sheep

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.\n

Additional Info

Recognizes human EGFR. Species sequence homology: Chicken, mouse and rat.

Read more on Supplier website

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

Reactivities

Hum, Mouse

More info

Applications

ELISA

Hosts

Mouse

More info
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