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eIF2(alpha) (I45) pAb

eIF2(alpha) (I45) pAb

Cat no: BS3651


Supplier: Bioworld Technology, Inc.
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eIF2(alpha), also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2(alpha) controls the rate of tRNA translation. When eIF2(alpha) is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2(alpha) is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.
Catalogue number: BS3651
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P05198
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 11-60 of Human eIF2(alpha).
Species: eIF2(alpha) (I45) pAb detects endogenous levels of eIF2(alpha) protein.
Molecular weight: ~ 38 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha; EIF2A; EIF2S1
Additional info: For research use only, not for use in diagnostic procedure.

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