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eIF2? (phospho Ser51) Polyclonal Antibody

Cat no: ABP50305

eIF2? (phospho Ser51) Polyclonal Antibody

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha(Ernst et al., 1987 [PubMed 2948954]).

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SPECIFICATIONS

Catalog Number

ABP50305

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Gene Id

1965

Isotype

Rabbit IgG

Accession

P05198

Clonality

Polyclonal

Concentration

1 mg/ml

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