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EIF2AK3 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, HsPEK, PEK, PERK)

Cat no: E8949-17C

EIF2AK3 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, HsPEK, PEK, PERK)

EIF2AK3, a Translational Control type protein kinase, is believed to mediate phosphorylation of eIF2-alpha in response to malfolded proteins in the endoplasmic reticulum. Diabetes and Wolcott-Rallison syndrome (WRS) are linked to the mutations in the EIF2AK3 gene.\n\nApplications: \nSuitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:500-1:3000\nImmunohistochemistry (Formalin fixed paraffin embedded): 1:400\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

E8949-17C

Size

50ul

Applications

IF, IHC, IP, WB

Hosts

Rabbit

Reactivities

Mouse

Form

Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.

P Type

Pab

Purity

Serum

Additional Info

Recognizes mouse EIF2AK3.

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