Home  >  Products  >  eIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C, eIF3c, Eukaryotic Translation Initiation Factor 3 Subunit 8, eIF3 p110, EIF3S8, EIF3CL)2
eIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C, eIF3c, Eukaryotic Translation Initiation Factor 3 Subunit 8, eIF3 p110, EIF3S8, EIF3CL)2

eIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C, eIF3c, Eukaryotic Translation Initiation Factor 3 Subunit 8, eIF3 p110, EIF3S8, EIF3CL)2

Cat no: E2238-01B

Supplier: United States Biological
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EIF3C is a 913aa containing RNA associated protein that binds to the 40S ribosomal unit and promotes and stabilizes the binding of methionyl-tRNAi and mRNA and is thus an important protein involved in protein synthesis. EIF3C, a member of the EIF-3 subunit C family with a PCI domain, is a component of the EIF3 multiprotein complex composed of at least 13 different subunits and is known to interact with EIF3K. EIF3C and EIF3CL are found in a head-to-tail orientation on slightly different chromosomal localizations and separated by a few genes. Ubiquitous expression is seen in most of the tissues. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: E2238-01B
Reactivities: Human, Mouse, Rat, Bovine, Canine
Hosts: Rabbit
Applications: ELISA
Size: 100ul
Form: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum
References: 1. Asano, K. et al. J. Biol. Chem. 272:1101-1109 (1997). 2. Molina, H. et al. Proc Natl Acad Sci USA. 104:2199-2204 (2007).
Additional info: Recognizes human eIF3C. Species Crossreactivity: chimpanzee, bovine, canine, mouse, rat. Species sequence homology: equine, xenopus.

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