Home  >  Products  >  eIF3G (Eukaryotic Translation Initiation Factor 3 Subunit G, eIF3g, Eukaryotic Translation Initiation Factor 3 RNA-binding Subunit, eIF-3 RNA-binding Subunit, Eukaryotic Translation Initiation Factor 3 Subunit 4, eIF-3-delta, eIF3 p42, eIF3 p44, EIF3S4)
eIF3G (Eukaryotic Translation Initiation Factor 3 Subunit G, eIF3g, Eukaryotic Translation Initiation Factor 3 RNA-binding Subunit, eIF-3 RNA-binding Subunit, Eukaryotic Translation Initiation Factor 3 Subunit 4, eIF-3-delta, eIF3 p42, eIF3 p44, EIF3S4)

eIF3G (Eukaryotic Translation Initiation Factor 3 Subunit G, eIF3g, Eukaryotic Translation Initiation Factor 3 RNA-binding Subunit, eIF-3 RNA-binding Subunit, Eukaryotic Translation Initiation Factor 3 Subunit 4, eIF-3-delta, eIF3 p42, eIF3 p44, EIF3S4)

Cat no: E8949-36D

Supplier: United States Biological
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eIF3G is an RNA-associated protein involved in protein synthesis. It is a member of the eIF-3 subunit G family and the largest of the eukaryotic translation initiation factor family with eukaryotic translation initiation factor-3 (eIF3) being a multiprotein complex composed of at least 13 different subunits. eIF3G has a RRM (RNA recognition motif) domain and is known to interact with eIF3K. The function of eIF3G is to bind to the 40S ribosomal subunit and promote the binding of methionyl-tRNAi and mRNA. This subunit of eukaryotic translation initiation factor-3 also binds to the 18S rRNA. It is ubiquitously expressed in most tissues. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 4-5ug/ml Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: E8949-36D
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A affinity chromatography.
References: 1. Bandyopadhyay, A. et al. Nucleic Acids Res. 27:1331-1337 (1999). 2. Block, KL. et al. J. Biol. Chem. 273:31901-31908 (1998). 3. Beausoleil, SA. et al. Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135 (2004). 4. Mayeur, GL. et al. Eur. J. Biochem. 270:4133-4139 (2003).
Additional info: Recognizes human eIF3G. Species Crossreactivity: chimpanzee, rhesus monkey. Species sequence homology: bovine, mouse, opossum, rat, xenopus, zebrafish.

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