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eIF4A1 Monoclonal Antibody

Cat no: ABM40136

eIF4A1 Monoclonal Antibody

eIF4A1 is a 406 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family and eukaryotic initiation factor-4A subfamily with a helicase ATP-binding domain and a helicase C-terminal domain. eIF4F eukaryotic translation initiation complex is formed by the association of eIF4A1 with eIF4E and eIF4E kinase (MNK1), eIF4B, eIF4G, PABPC1. It is closely related to eIF4A2. eIF4A1 is a eukaryotic translation initiation factor involved in protein translation/synthesis where it helps in unwinding the secondary structure of RNA in the 5'-UTR of mRNAs, cap recognition, and is necessary for efficient binding mRNA to the 40S small ribosomal subunit, as well as subsequent scanning for the initiator codon. Ubiquitous expression of the enzyme eIF4A1 is seen in most tissues.

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SPECIFICATIONS

Catalog Number

ABM40136

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Gene Id

1973

Isotype

Mouse IgG1

Accession

P60842

Clonality

Monoclonal

Concentration

1 mg/ml

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