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eIF4G (eukaryotic translation initiation factor 4 gamma, 1, KFZp686A1451, EIF4F, EIF4G, eIF-4G1, eIF-4G 1, eIF-4-gamma 1, EIF4GI, Eukaryotic translation initiation factor 4 gamma 1, p220)

Cat no: E8949-55B

Supplier: United States Biological

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eIF4F is a translation initiation factor containing three subunits: eIF4A, eIF4E, and eIF4G. This complex is a key component in promoting ribosomal binding to the mRNA. eIF4G interacts with both eIF4A and eIF4E though its carboxy and amino terminal domains, respectively. eIF4E binds to the cap structure of the mRNA, while the ATP-dependent RNA helicase eIF4A unwinds the secondary structure of the 5

Catalogue number:	E8949-55B
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunofluorescence, Western Blot
Size:	100ul
Form:	Supplied as a liquid, 0.05% NaN3
P type:	Pab
Purity:	Serum.
References:	1. Lejeune, F. et al. (2004). Nature Struct & Mol Biol. 11(10):992-1000. 2. Haghighat, A. et al. (1997) JBC. 272(35):21677-21680.
Additional info:	Recognizes human eIF4G at its N-terminal region. Species Crossreactivity: mouse.

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eIF4G (eukaryotic translation initiation factor 4 gamma, 1, KFZp686A1451, EIF4F, EIF4G, eIF-4G1, eIF-4G 1, eIF-4-gamma 1, EIF4GI, Eukaryotic translation initiation factor 4 gamma 1, p220)

Cat no: E8949-55B

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