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Elastase, Neutrophil (ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1)

Elastase, Neutrophil (ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1)

Cat no: E2230-13G

Supplier: United States Biological
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The primary role of neutrophils is to destroy any foreign particles, either by phagocytosis or by release of bacteriostatic agents. Neutrophils contain high concentrations of the serine proteinases neutrophil elastase that is stored in intracellular vacuoles termed the azurophilic granules.
Catalogue number: E2230-13G
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry
Size: 200ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
Alternative names: Elastase, Neutrophil Expressed
References: 1. Durant, S. et al. (2004) Apoptosis-induced proteinase 3 membrane expression is independent from degranulation. J. Leukoc. Biol. 75(1): 87-98. 2. Davies, P.L. et al. (2008) Monoclonal anti-neutrophil elastase antibody characterisation: ability to block function, detect free versus serpin-complexed enzyme and stain intracellular granules. J Immunol Methods. 336: 175-82.
Additional info: Recognizes human neutrophil elastase.

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