ELF5 (E74-like Factor 5, ESE2, Ets Domain TF)

This protein is a member of an epithelium-specific subclass of the Ets transcription factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it may regulate a number of epithelium-specific genes found in tissues containing glandular epithelium. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

E2239-40

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Oettgen P et al. (1999) J Biol Chem 274:29439-52.

Additional Info

This antibody is expected to recognize both reported isoforms (as represented by NP_001413; NP_938195) Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse, Rat, Human (100% identity with immunogen) and Mouse (100% identity with immunogen) due to sequence homology.