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ELG-1 (ATP(GTP)-binding protein, Chromosome fragility associated gene)

Cat no: 168162

ELG-1 (ATP(GTP)-binding protein, Chromosome fragility associated gene)

ELG1 (also known as ATP(GTP)-binding protein or chromosome fragility associated gene 1) is involved in a novel RFC complex that is probably involved in DNA damage and repair by ensuring replication fidelity. This detects a band at about 120kD in Hela, A431, Jurkat and HEK193 cells. This corresponds to the band size seen in Kanellis P et al. It remains unclear why the band size detected is much less than the 207kD predicted in the protein sequence corresponding to CACC44537.2 (Q96QE3), but as our results correspond to those seen in Kanellis P et al. it is likely that the 120kD target is ELG1.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:3000-1:15,000\nWestern Blot: 1:500-1:2000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

168162

Size

100ug

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.

P Type

Pab

Purity

Purified by Protein A/G affinity chromatography.

Isotype

IgG

Additional Info

Recognizes human ELG1.

Alternative Names

ATP(GTP)-binding protein, Chromosome fragility associated gene

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