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EliKine™ Mouse CCL2 ELISA Kit

Cat no: KET7001

EliKine™ Mouse CCL2 ELISA Kit

CCL2 is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). This chemokine is produced predominantly by macrophages and endothelial cells and is a potent chemotactic factor for monocytes as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa.CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. Expression of this proinflammatory chemokine is increased in atherosclerotic lesions, and inhibition of its expression or that of its receptor, CC chemokine receptor 2 (CCR2), reduces the extent of atheroma formation in hypercholesterolemic mice.

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SPECIFICATIONS

Catalog Number

KET7001

Size

48T, 96T, 96T*5

Applications

ELISA

Reactivities

Mouse

Gene Id

20296

Accession

P10148

Additional Info

EliKineв„ў Mouse CCL2 ELISA Kit has high sensitivity and excellent specificity for detection of Mouse CCL2. No significant cross-reactivity or interference between Mouse CCL2 and analogues was observed.

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