Home  >  Products  >  Elongin A (Elongin-A, Ela1, EloA, Elongin 110kD Subunit, RNA Polymerase II Transcription Factor SIII Subunit A1, SIII, SIII p110, Transcription Elongation Factor B (SIII) Polypeptide 3 110kD, TCEB3, TCEB3A)
Elongin A (Elongin-A, Ela1, EloA, Elongin 110kD Subunit, RNA Polymerase II Transcription Factor SIII Subunit A1, SIII, SIII p110, Transcription Elongation Factor B (SIII) Polypeptide 3 110kD, TCEB3, TCEB3A)

Elongin A (Elongin-A, Ela1, EloA, Elongin 110kD Subunit, RNA Polymerase II Transcription Factor SIII Subunit A1, SIII, SIII p110, Transcription Elongation Factor B (SIII) Polypeptide 3 110kD, TCEB3, TCEB3A)

Cat no: E2250-01A

Supplier: United States Biological
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TCEB3 (Elongin A) is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: E2250-01A
Reactivities: Human
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Species Crossreactivity: Human.

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