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EMSY (BL1050, C11orf30, GL002)

Cat no: E2262-01B


Supplier: United States Biological
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EMSY binds BRCA2 within a region (exon 3) deleted in cancer. EMSY is capable of silencing the activation potential of BRCA2 exon 3, associates with chromatin regulators HP1 and BS69, and localizes to sites of repair following DNA damage. Its levels are amplified in breast and ovarian cancer. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:5000-1:20,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: E2262-01B
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7-8, containing 0.09% sodium azide
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography
Alternative names: Chromosome 11 Open Reading Frame 30, FLJ90741
Additional info: Recognizes human EMSY protein. Reactivity with mouse is unknown, but mouse EMSY is well conserved with human EMSY at the site to which the epitope maps

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