Encephalopsin, a member of the Opsin subfamily of GPCRs, is similar in sequence to vertebrate retinal and pineal opsins and may affect photoreception in the brain. Encephalopsin expression has been documented in various brain tissues, including the preoptic area and paraventricular nucleus of the hypothalamus, cerebral cortex, cerebellar Purkinje neurons, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord. ESTs have been isolated from human blood, breast, cervix, colon, germ cell, head/neck, kidney, lung, pancreas, placenta, prostate, skin, testis, and uterus cancer libraries, as well as from normal human blood, brain, eye, heart, kidney, liver, liver/spleen, ovary, placenta, prostate, skin, testis, and B-cell/lung/testis libraries.
Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (paraffin): 5-8ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control:
Human Brain, Neuron and gilla.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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