Endonuclease G (EndoG)

Supplier:

United States Biological

Cat no: E2291-40A

Endonuclease G (EndoG)

Recommended Secondary Reagents: Sheep anti Rabbit IgG (Aff. Pur.): HRP\n\nApplications:\nWestern Blotting: 1-2ug/ml\nOptimal working dilutions to be determined by researcher.\n\nWestern Blotting: Detects a band of approximately 35kD in HepG2 and 3T3 cell lysates.

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SPECIFICATIONS

Catalog Number

E2291-40A

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS with 0.02% sodium azide.

P Type

Pab

Purity

Purified IgG was prepared from whole serum by affinity chromatography.

Isotype

IgG

References

1. Li Ly, et al., (2001) Nature 412:95-99.

Additional Info

Recognizes endonuclease G (endoG), a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis endoG i reported to act independently of caspases and may represent a caspase independent apoptotic pathway initiated from the mitochondria. Species Crossreactivity: Human. Expected crossreactivity from sequence similarity mouse, rat.

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SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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