Endothelin B Receptor Antibody

Cat no: 251852

Supplier: ABBIOTEC

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Description
Additional Information

The endothelin receptor B (EDNRB) is a non-specific receptor for endothelin 1, 2 and 3. EDNRB mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Defects in the endothelin receptor B are a cause of Waardenburg syndrome type 4A (WS4A), also known as Waardenburg-Shah syndrome. WS4A is characterized by the association of Waardenburg features (depigmentation and deafness) and the absence of enteric ganglia in the distal part of the intestine (Hirschprung disease).

Catalogue number:	251852
Reactivities:	Human, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P24530
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human endothelin B receptor.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA, 0.05% thimerosal with 0.5% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Endothelin B receptor; ET-BR; ET-B; Endothelin receptor non-selective type; EDNRB; ETRB