Innoprot HiTSeeker EDNRA Cell Line has been designed to assay compounds or analyze their capability to modulate Endothelin Receptor type A. When Endothelin I binds to the EDNRA a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (Ca). This cell line has been validated measuring Calcium increase in the cytosol. The high reproducibility of this assay allows monitoring Endothelin Receptor type A